He made his debut at the Basel theatre with the opera Macbeth by Giuseppe Verdi. Between 2001 and 2004 he worked as the Principal Conductor and Assistant to Chief Conductor Miguel Gomez Martinez at the Bern Theatre. In 2004 he became a position of Chief Conductor at the same institution, and he stayed in this role until 2013. From 2007 to 2011 he was also the Artistic Director of this house. He conducted 37 opera premieres in Bern and more than 60 productions, symphonies and gala concerts. The most important among them is most certainly a project by Swiss television channel SF1, which broadcast live performance of the opera La Boheme across the whole of Western Europe. Production and DVD received the most important TV award in Switzerland Golden Rose Award.

​Between 2006 and 2009 he was a Regular Guest Conductor at the Stuttgart State Theatre (Staatstheater Stuttgart) where he conducted operas Madama Butterfly, Tosca and Norma. In 2006 he had a debut at the most important opera festival in Switzerland, in Avenches, with Verdi’s opera Il Trovatore. Between 2009 and 2011 he performed at Teatro Massimo in the Italian city Palermo, where he conducted opera premieres Puritani, Aida and La Gioconda. At that time, he performed at the prestigious Savonlinna Festival in Finland, where he conducted operas Puritani and Tosca. From 2012 to 2014 he was a Permanent Guest Conductor at Aalto Theater in Essen, Germany where he conducted opera premieres Eugene Onegin, Aida and I Masnadieri. At the same time he was a Guest Conductor at Croatian National Theatre in Zagreb where he conducted opera premieres Jenufa and Tosca, and also Carmen at the National Theatre in Belgrade. In Rovigo he directed the operetta The Merry Widow. From 2013 until 2019 he assumed the role of Artistic Director and Chief Conductor of one of the biggest opera houses in America, Palace of Fine Arts (Teatro de Bellas Artes) in Mexico City, where he conducted more than 20 productions and gala concerts. Srba Dinić is also the Chief Conductor of a renowned chamber orchestra St. George Strings Orchestra from Serbia, and he has worked with them since 2013. He made his debut in Braunschweig in Germany, with premiere of the opera Andrea Chenier. That September, he opened a new season in the same city with two symphony concerts. From the concert season 2017/2018 he is General Music Director.

​Throughout most of his career, Dinić collaborated with the greatest opera performers in the world such as Anna Netrebko, Diana Damrau, Aihnoa Arteta, Desiree Rancatore, Agnes Baltza, Silvia dalla Benetta, Ramon Vargas, Carlo Colombara, Hector Sandoval, Salvatore Licitra, Francisco Araiza, Željko Lučić, Milijana Nikolić, Ivo Pogorelić, Radovan Vlatković, Stefan Dor, Nemanja Radulović, Leticia Moreno, Roman Simović, Yuri Bashmet, Narek Akhnazaryan, Aleksandar Madžar and many others.

​In the field of symphony music, Srba Dinić collaborated with many notable orchestras around the world, such as Müncher Symphoniker, Staatsorchester Stuttgart, Staatsorchester Braunschweig, Essener Philharmoniker, Württembergische Philharmonie, Nürnberger Symphoniker, Berner Sinfonieorchester, Basel Sinfonieorchester, Orchestra di Verona, Orchestra di Teatro Massimo, Orquesta de Valencia, Beograde philharmonic orchestra, St. George Strings Orchestra, Hungarian Radio Symphony Orchestra, Orqoesta filarmonica de Ciudad Mexico, Orquesta filarmonica de Universidad autonoma de Mexico, Orquesta de Mineria from Mexico City, Shanghai symphony orchestra, Taipeh symphony orchestra, Radio Television of Serbia Symphony Orchestra and many others.

Since 2023, he has been working as an associate professor at the Faculty of Music in Belgrade.

From the season 2025, he is Chief Conductor of the RTS Symphony Orchestra and Choir.

Srba Dinić received an award from the Ministry of Culture of Republic of Serbia for spreading and promoting Serbian culture in the world.